Use dynamo script with custom nodes in Pyrevit

I know how to use Dynamo script with Pyrevit, but my question is if i am using custom node in the dynamo script, and i put this custom node file in the same folder with the dynamo script in Pyrevit directory, can the script run properly even if the dynamo package of the custom node is not loaded in the dynamo?
i mean, can dynamo read the custom node if both are in the same folder ?